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What is BPC-157 + TB-500
It is a combination of two peptides: BPC-157 – a stable fragment of a protein from gastric secretion and TB-500 – a fragment of thymosin beta-4. Both substances are tested in the field of tissue regeneration, and in combination an enhanced synergistic effect is expected.
Researched effects and interesting facts
- Regeneration: synergistic support for the recovery of muscles, tendons and nerve endings
- Angiogenesis: support of the vascular network and blood circulation
- Anti-inflammatory effects: reduction of local and systemic inflammation
- Gastroprotective effect: restoration of damaged mucous membranes and prevention of ulcers
- Neuroprotection: protection and support of mitochondrial activity in neurons
How does the combination work?
BPC-157 supports angiogenesis, the restoration of mucous membranes and the nervous system, while TB-500 stimulates the formation of actin and the restoration of muscle or ligament structures. The combination is being studied in cases of soft tissue damage, inflammatory processes or neurological diseases.
Dosage in studies
- Dose: 200–800 μg (BPC‑157), 2–5 mg (TB‑500)
- Form: subcutaneously or intramuscularly, sometimes topically
- Frequency: daily or weekly
- Duration: 2–6 weeks
BPC-157 and TB-500 are two synthetic peptides known for their research potential in the field of tissue regeneration, healing and protection. In this combined form, they are being studied primarily for their synergistic effects on muscles, tendons, blood vessels and the nervous system.
| Parameter | Value |
|---|---|
| Form | Lyophilized powder |
| Content | 5mg BPC-157 + 5mg TB-500 |
| Concentration (assay) | BPC-157: 5.87mg / TB-500: 5.12mg |
| Packaging | Glass bottle with cap |
| Storage | 2–8°C, protected from light |
| Molecular formula | C62H98N16O22 + C212H350N56O78S |
| Molecular weight | 1419.535g·mol⁻¹ + 4963.37g·mol⁻¹ |
| IUPAC name | Body Protective Compound + Thymosin Beta-4 Acetate |
| CAS number | 141645-16-1 |
| Other names | BPC157, PL 14736, TB500, thymosin beta-4 |
In laboratory studies, BPC-157 and TB-500 have been linked to research in areas such as:
- regeneration of muscles, tendons, ligaments, and blood vessels,
- angiogenesis and wound healing,
- reduction of inflammation and oxidative stress,
- protection of the digestive tract and nerve cells,
- repair of damaged tissues after injuries or surgeries.
Possible side effects
- Mild irritation at the injection site
- Occasional headache, fatigue
- There are no systemic toxic effects in the tested doses
Sources
- Sikiric, P. et al. – BPC‑157: Healing and biological roles (2018)
- Goldstein, A.L. et al. – Thymosin beta‑4 in tissue repair (2005)
- Chang, C.H. et al. – Peptides in tendon healing (2011)
- Wang, Y. et al. – Muscle regeneration peptides review (2017)
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