MK-677, also known as Ibutamoren, is an oral secretagogue – a compound that stimulates the natural release of growth hormone (GH) and IGF-1. In this guide, we’ll explain how MK-677 works, its potential benefits and risks, who may consider it, and what to watch out for if you decide to use it.
What is MK-677?
MK-677 (Ibutamoren) is a non-peptide agonist of ghrelin receptors (GHS-R1a), stimulating the pituitary gland to release more growth hormone. Unlike peptides or injectable HGH, MK-677 is oral – “needle-free” – making it far more practical.
While often grouped with SARMs, it is not technically a SARM (it does not act on the androgen receptor). Instead, it’s a GH secretagogue. For the actual product, check out MK-677 (Ibutamoren) in our shop.
How MK-677 Works
- Ghrelin receptor binding: mimics ghrelin (“hunger hormone”), signaling the pituitary to release GH.
- GH → IGF-1: higher GH usually means increased serum IGF-1, linked to tissue growth and recovery.
- Circadian pattern: MK-677 promotes pulsed GH release, more physiological than the flat curve of exogenous HGH.
Potential Benefits of MK-677
- Recovery & sleep: improved recovery after training, sometimes deeper REM sleep.
- Body composition: supports lean muscle growth and muscle retention in a deficit.
- Bones & joints: GH/IGF-1 impact connective tissues and bone metabolism.
- Convenience: oral, no mixing or injections.
Note: MK-677 is not a medicine. Results depend on dosage, nutrition, and training.
Risks and Side Effects
- Increased appetite: common due to ghrelin stimulation, which can challenge dieting.
- Water retention / bloating: especially early on; often temporary.
- Drowsiness / vivid dreams: for some a benefit, for others disruptive.
- Blood sugar markers: possible impact on insulin sensitivity – monitor labs.
- Contraindications: not suitable for pregnant/breastfeeding women or certain medical conditions.
Dosage and Usage
- Common range: 10–25 mg daily, often ~20 mg.
- Timing: evening (if it makes you sleepy) or morning (if evening dose disrupts sleep).
- Cycle length: 8–12 weeks; advanced users sometimes 3–6 months, followed by a break and bloodwork.
- Titration: start low (10–12.5 mg), then adjust upward based on response.
For a trusted option, see our MK-677 (Ibutamoren) product.
Comparison: MK-677 vs. Alternatives
| Compound | Form | Pros | Cons |
|---|---|---|---|
| MK-677 (Ibutamoren) | Oral | Needle-free, boosts GH/IGF-1, easy dosing | Appetite, water retention, insulin sensitivity |
| HGH (exogenous) | Injectable | Direct GH dosing | Needles, legality, high cost |
| Peptides (GHRP/Ipamorelin/CJC) | Injectable | Targeted GH stimulation | Mixing, storage, injections |
Legal Status and Doping
The availability of MK-677 varies by country and intended use. In competitive sports it is banned under anti-doping rules. Always check your federation’s current banned substance list.
FAQ: MK-677
Is MK-677 a SARM?
How soon will I notice effects?
Do I need PCT after MK-677?
Morning or evening dosing?
Will I gain fat on MK-677?
See our MK-677 product for details and ordering.
Summary & Recommendations
- MK-677 provides a convenient way to boost natural GH/IGF-1 release without injections.
- Practical benefits include recovery, sleep, and muscle retention.
- Main risks: appetite, water retention, and possible blood sugar changes – dose carefully and monitor labs.
- Consider health status and sports regulations before use.
Ready to try? Choose MK-677 (Ibutamoren) from us – fast delivery and verified origin.



